To increase the effectiveness of treatment of hypotonic functional dysphonia using physiotherapy in patients with neurovegetative disorders.
The study included 42 patients, aged from 25 to 64 years, with disturbed vocal function, which included anamnestic analysis, an objective study of ENT organs by conventional methods, a video stroboscopy of the larynx, a cytological study of smears from the laryngeal mucosa, and the determination of the functional state of the autonomic nervous system (ANS).
The clinical-physiological study of VNS shows neurovegetative dysfunction (inadequate autonomic support of activity) in 10 patients. In these patients, the traditional conservative treatment was ineffective. Acupuncture used for treatment of neurovegetative disorders in these patients significantly improves the results of traditional treatment.
The results indicate an increase in the effectiveness of physiotherapy treatment (reflexotherapy using magnetic-infrared laser radiation and acupuncture) of ANS condition. These measures can be carried out in conjunction with traditional methods of treatment or in the case of their low efficiency.
The results indicate an increase in the effectiveness of physiotherapy treatment (reflexotherapy using magnetic-infrared laser radiation and acupuncture) of ANS condition. https://www.selleckchem.com/products/TW-37.html These measures can be carried out in conjunction with traditional methods of treatment or in the case of their low efficiency.To comparare socio-demographic and clinical characteristics of patients with the first depressive episode and recurrent depression.
Three hundred and twenty one patients with unipolar depression, including 96 patients with first depressive episode and 225 patients with recurrent depression, were examined using clinical and psychometric methods.
There were differences in clinical characteristics between groups but such factors as gender, marital status, level of education, family history of mental disorders and personality were similar. With each new episode of recurrent depression, the next episode tends to be more severe with more intense pessimistic and suicidal thoughts but fewer anxiety and complaints of depressive mood that affects the differences and requires further research, especially considering the effect of therapy.
There were differences in clinical characteristics between groups but such factors as gender, marital status, level of education, family history of mental disorders and personality were similar. With each new episode of recurrent depression, the next episode tends to be more severe with more intense pessimistic and suicidal thoughts but fewer anxiety and complaints of depressive mood that affects the differences and requires further research, especially considering the effect of therapy.To analyze the effectiveness of the developed technique of ?3D audio-visualization? in restoring the motor function of the upper limb in the acute period of stroke.
The study included 20 patients in the acute period of stroke. All patients had impaired motor function of the upper limb in the form of paresis of the proximal muscle groups. The control group was enrolled according to standard methods. The treatment was well tolerated, there were no adverse effects.
In the study group, a more complete restoration of the motor function of the upper limb is observed compared with the control group. There is also a positive effect of the proposed technique on patients in the acute period of stroke.
The prospective and cost effective technique is suggested. It can be also used by the patient in the outpatient rehabilitation phase.
The prospective and cost effective technique is suggested. It can be also used by the patient in the outpatient rehabilitation phase.To estimate the incidence of epileptic seizures in patients with glial and metastatic brain tumors and to identify clinical and morphological risk factors for epileptic seizures in patients with glial and metastatic brain tumors.
The study included 225 (88.6%) patients with glial brain tumors and 29 patients (11.4%) with metastatic tumors.
Statistically significant differences in the incidence of epileptic seizures depending on age, histological characteristics of the tumor, degree of malignancy, tumor localization, involvement of the cerebral cortex, the presence of the midline shift were obtained.
Epilepsy and epileptic seizures was found to develop in 51.11% and 24.14% of cases in glial and metastatic brain tumors, respectively. Risk factors for developing epileptic seizures include younger age (up to 57 years), histological characteristics corresponding to diffuse astrocytomas, anaplastic astrocytomas, oligodendrogliomas, oligoastrocytomas, grade I-III malignancy, lesion of the temporal lobe, invoover 57, histological characteristics corresponding to glioblastomas and metastatic tumors, grade IV malignancy, subcortical localization of the tumor, damage to the occipital lobe, involvement of the commissural pathways, subtentorial localization of the tumor, the absence of lesions of the temporal and frontal lobes of the brain, the involvement of both brain hemispheres, damage to two or more brain lobes, the presence of a midline shift.To systemize the neurological manifestations of COVID-19.
A systematic computer analysis of all currently available publications on the neurological manifestations of COVID-19 (2374 publications in PUBMED) using algorithms of topological data analysis was performed.
A complex of interactions between SARS-CoV-2 infection, metabolic disorders of neurotransmitters (acetylcholine, dopamine, serotonin and GABA), enkephalins and neurotrophins, micronutrients, chronic and acute inflammation, encephalopathy, cerebral ischemia and neurodegeneration, including demyelination, was described. The most common neurological manifestation of COVID-19 is anosmia/ageusia arising as a result of ischemia, neurodegeneration, and/or systemic elevation of proinflammatory cytokine levels. COVID-19 provokes ischemic stroke, Guillain-Barré syndrome, polyneuropathy, encephalitis, meningitis and parkinsonism. Coronavirus infection significantly aggravates the course of multiple sclerosis and myopathies. Possible roles of the human virome in the neuropathophysiology of COVID-19 are considered.